{ "$schema": "https://ui.shadcn.com/schema/registry-item.json", "name": "myocardial-infarction", "title": "Myocardial infarction", "description": "An anterior ST-elevation myocardial infarction on the heart: the blocked left anterior descending artery and the wall it supplies, from occlusion through the acute phase to a healed scar, with the ECG, troponin and echo at each stage. Model licensed CC BY 4.0.", "registryDependencies": [ "@organui/disease-viewer", "@organui/heart" ], "files": [ { "path": "registry/base-nova/myocardial-infarction/myocardial-infarction.tsx", "content": "import { diseaseModel, type Disease } from \"@/components/disease-model\"\nimport {\n DiseaseViewer,\n type DiseaseViewerProps,\n} from \"@/components/disease-viewer\"\nimport { heartModel } from \"@/components/heart\"\n\n// An anterior ST-elevation myocardial infarction: the left anterior\n// descending artery, a branch of the left coronary, blocks and the anterior\n// wall and septum it supplies die and scar.\nexport const myocardialInfarction: Disease = {\n name: \"Myocardial infarction\",\n code: \"I21.0\",\n summary:\n \"A clot on a ruptured plaque blocks a coronary artery and the heart muscle it supplies dies. Every minute until the artery is reopened costs muscle.\",\n scales: [\n {\n id: \"heart\",\n label: \"Heart\",\n model: heartModel,\n findings: {\n \"left-coronary\": {\n label: \"Left coronary artery (LAD)\",\n affected: true,\n description:\n \"The culprit is its left anterior descending (LAD) branch: a cholesterol plaque ruptures and a clot forms on it, blocking the artery. Emergency angioplasty (PCI) reopens it with a stent.\",\n },\n \"ventricular-wall\": {\n affected: true,\n description:\n \"The anterior wall and septum, which the LAD supplies. Starved of oxygen, the muscle stops contracting within a minute. Cells start to die after about 20 minutes, from the inner layer outwards, so reperfusion within hours saves the outer wall.\",\n },\n \"left-ventricle\": {\n affected: true,\n description:\n \"With part of its wall still, the left ventricle empties less with each beat. A large infarct causes cardiogenic shock.\",\n },\n \"right-coronary\": {\n affected: false,\n description:\n \"Supplies the inferior wall and is patent here; its occlusion causes an inferior infarction instead.\",\n },\n \"right-ventricle\": {\n affected: false,\n description:\n \"Spared in anterior infarction. Right ventricular infarction comes with a proximal right coronary occlusion.\",\n },\n \"ascending-aorta\": {\n affected: false,\n description:\n \"Not involved. An aortic dissection can mimic infarction and must be excluded before clot-busting drugs.\",\n },\n },\n },\n ],\n stages: [\n {\n id: \"occlusion\",\n label: \"Occlusion\",\n summary:\n \"The first hours. ST elevation on the ECG means the artery is blocked; reopen it with PCI within 120 minutes of diagnosis.\",\n },\n {\n id: \"acute\",\n label: \"Acute\",\n summary:\n \"Days 1 to 7. Dead muscle is soft while white cells clear it, and the wall is weakest from day 3 to day 7.\",\n findings: {\n heart: {\n \"left-coronary\": {\n label: \"Left coronary artery (LAD)\",\n affected: true,\n description:\n \"Opened and stented. Two antiplatelet drugs stop a clot forming on the new stent.\",\n },\n \"ventricular-wall\": {\n affected: true,\n description:\n \"In the infarcted anterior wall and septum, neutrophils, then macrophages, clear the dead muscle. Rarely the softened wall or septum ruptures, most often between days 3 and 7.\",\n },\n \"left-ventricle\": {\n affected: true,\n description:\n \"The still wall lets a clot form at the apex, which can embolise, and arrhythmias are common in the first days.\",\n },\n },\n },\n investigations: [\n { name: \"Troponin\", result: \"Peaks\", flag: \"high\" },\n { name: \"ECG\", result: \"Q waves forming\", flag: \"abnormal\" },\n { name: \"Echo\", result: \"Anterior akinesia\", flag: \"abnormal\" },\n { name: \"LV ejection fraction\", result: \"Reduced\", flag: \"low\" },\n ],\n },\n {\n id: \"healed\",\n label: \"Healed\",\n summary:\n \"From about six weeks. Collagen scar has replaced the muscle; treatment protects the rest of the heart and prevents the next event.\",\n findings: {\n heart: {\n \"left-coronary\": {\n label: \"Left coronary artery (LAD)\",\n affected: true,\n description:\n \"Stented. Statins, antiplatelets and stopping smoking keep it and the other arteries open.\",\n },\n \"ventricular-wall\": {\n affected: true,\n description:\n \"The anterior wall and septum are now a thin collagen scar that does not contract. If it bulges with each beat it is a ventricular aneurysm.\",\n },\n \"left-ventricle\": {\n affected: true,\n description:\n \"Remodelling: the ventricle dilates to keep its output. ACE inhibitors and beta blockers limit it and heart failure.\",\n },\n },\n },\n investigations: [\n { name: \"Troponin\", result: \"Normal\" },\n { name: \"ECG\", result: \"Persistent Q waves\", flag: \"abnormal\" },\n { name: \"LV ejection fraction\", result: \"Reduced\", flag: \"low\" },\n { name: \"LDL cholesterol\", result: \"Target < 1.4 mmol/L\" },\n ],\n },\n ],\n investigations: [\n { name: \"ECG\", result: \"ST elevation V1–V4\", flag: \"abnormal\" },\n { name: \"Troponin\", result: \"Rising\", flag: \"high\" },\n { name: \"Echo\", result: \"Anterior hypokinesia\", flag: \"abnormal\" },\n { name: \"Angiogram\", result: \"LAD occluded\", flag: \"abnormal\" },\n ],\n}\n\n/** The heart at occlusion, the stage the viewer opens on. */\nexport const myocardialInfarctionModel = diseaseModel(myocardialInfarction)\n\nexport type MyocardialInfarctionProps = Omit\n\nexport function MyocardialInfarction(props: MyocardialInfarctionProps) {\n return \n}\n", "type": "registry:component" } ], "docs": "Myocardial infarction docs: https://organui.com/docs/components/myocardial-infarction. It reuses the heart model, licensed CC BY 4.0 (https://dbarchive.biosciencedbc.jp/en/bodyparts3d/lic.html); keep the viewer's credit visible. Educational, not for diagnosis.", "categories": [ "disease", "cardiovascular" ], "type": "registry:component" }